LysoTracker signal intensity

1. Cellular senescence is associated with LysoTracker signal intensity in humans.

   “Representative outcomes show increased LysoTracker signal and expanded lysosome-enriched regions in late-passage cultures compared to early-passage controls, consistent with lysosomal remodeling during senescence.”

   ReviewLate-passage cultures compared with early-passage controlsIMR-90 human lung fibroblasts

   Lysosomal Profiling with LysoTracker for Quantitative Assessment of Cellular Senescence in Human Fibroblasts

   bioRxiv : the preprint server for biology·17 Apr 2026Preprint

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