Lipid accumulation product index

There are 5 papers on lipid accumulation product index in aging research: 1 trial and 4 observational studies in people. The newest story, Oct 26, 2026: “Cardiovascular aging score linked to future cardiovascular risk”.

5 papers study it4 more mention it5 findings

1 new paper in 30 daysSee all 9

“In addition, LAP and CVAI are also good at predicting MetS.”

Predicting metabolic syndrome by obesity- and lipid-related indices in mid-aged and elderly Chinese: a population-based cross-sectional studyFrontiers in endocrinology2023doi:10.3389/fendo.2023.1201132

Human trial1
Humans4

Associations

5

Inflammation

upin humans1

1 study

Lipid accumulation product index is associated with inflammation in humans (p < 0.05).
“A higher LAP index was significantly correlated with serum inflammatory cytokines (p < 0.05).”
Humansn = 1,851
Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study
Journal of Alzheimer's disease : JADMar 13, 2026

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Vascular dementia

no changein humans1OR 1.12

1 study

Lipid accumulation product index is associated with vascular dementia in humans (OR 1.12, 95% CI 0.75-1.66).
“and 1.12 (0.75-1.66) for VaD”
Humansn = 5,670
Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study
Journal of Alzheimer's disease : JADMar 13, 2026

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Alzheimer's disease

upin humans1OR 1.4

1 study

Lipid accumulation product index is linked with a higher risk of Alzheimer's disease in humans (OR 1.40, 95% CI 1.05-1.86).
“1.40 (1.05-1.86) for AD”
Humansn = 5,670
Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study
Journal of Alzheimer's disease : JADMar 13, 2026

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Dementia

upin humans1OR 1.28

1 study

Lipid accumulation product index is linked with a higher risk of dementia in humans (OR 1.28, 95% CI 1.01-1.61).
“the LAP index was associated with multivariable-adjusted odds ratios of 1.28 (95% confidence interval: 1.01-1.61) for all-cause dementia”
Humansn = 5,670
Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study
Journal of Alzheimer's disease : JADMar 13, 2026

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Metabolic syndrome

upin humans1

1 study

Lipid accumulation product index predicts metabolic syndrome in humans.
“In addition, LAP and CVAI are also good at predicting MetS.”
Humansn = 9,457
Predicting metabolic syndrome by obesity- and lipid-related indices in mid-aged and elderly Chinese: a population-based cross-sectional study
Frontiers in endocrinologyJul 28, 2023

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Latest

4 papers in 12 months

ESC Congress 2026 AbstractOct 26

Cardiovascular aging score linked to future cardiovascular risk

Accelerated cardiovascular aging was linked to higher risk than normal aging, with a hazard ratio of 1.70 over a median 9.31 years.Accelerated cardiovascular aging was linked to higher risk than normal aging, with a hazard ratio of 1.70 over a median 9.31 years.

Cohort · 8,096 peopleCardiovascular disease

Journal of Alzheimer's DiseaseMar 13

Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study

Cross-sectional study of 5,670 peopleVascular dementia

International Journal of Cardiology Cardiovascular Risk and PreventionJul 21

Predicting circadian syndrome by obesity indices in middle-aged and older Chinese: evidence from the China Health and Retirement Longitudinal Study

Cross-sectional study of 9,265 peopleCircadian syndrome

Frontiers in EndocrinologyAug 14

Predicting metabolic syndrome by obesity- and lipid-related indices in mid-aged and elderly Chinese: a population-based cross-sectional study

Cross-sectional study of 9,457 peopleMetabolic syndrome

MenopauseOct 1

FADS1 and FADS2 polymorphism are associated with changes in fatty acid concentrations after calorie-restricted Central European and Mediterranean diets

Randomized trial in peopleDietary restriction

MedicineSep 19

Association between lipid accumulation product index (LAP index) and coronary artery disease risk: An observational study based on NHANES 2017-2020

Cross-sectional study of 7,860 peopleLipid Accumulation Product

FASEB JournalAug 28

Short Sleep Duration Is Positively Associated With Traditional and Non-Traditional Markers of Adiposity and Cardiometabolic Risk in Individuals at Secondary Healthcare: A Cross-Sectional Study

Cross-sectional study of 937 peoplePopulations

Nutrition, Metabolism, and Cardiovascular DiseasesFeb 4

Chinese visceral adiposity index as stronger predictor of hypertension and prehypertension in middle-aged and elderly Chinese adults: A comparative analysis with conventional adiposity indices

Cohort study in peopleChinese visceral adiposity index

BMC Cardiovascular DisordersApr 21

Predicting hypertension by obesity- and lipid-related indices in mid-aged and elderly Chinese: a nationwide cohort study from the China Health and Retirement Longitudinal Study

Cohort study of 4,423 peopleHypertension