LDL/HDL cholesterol ratio

1. Acarbose decreases LDL/HDL cholesterol ratio in humans (-26.7% with acarbose; +14.4% with placebo; unchanged with metformin).

   “Low-density lipoprotein (LDL)/high-density lipoprotein (HDL) cholesterol ratio increased by 14.4% with placebo, was unchanged with metformin, but decreased by 26.7% with acarbose.”

   Human trialType 2 diabetes; significant comparisons with placebo and metformin3 x 100 mg/day24 weeksn = 94

   Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study

   The American journal of medicine·1 Dec 1997

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