Brain
Alzheimer’s changes partly account for links to poorer thinking
Alzheimer’s changes statistically accounted for 13–29% of small-artery thickening’s links to poorer thinking, versus 64–91% for amyloid protein buildup in brain vessels.Alzheimer’s changes statistically accounted for 13–29% of small-artery thickening’s links to poorer thinking, versus 64–91% for amyloid protein buildup in brain vessels.
Cohort · 1,269 peopleMechanisms
Who was studied1,269 deceased adults with brain autopsies
What changedAlzheimer’s changes statistically accounted for approximately 13-29% of small-artery thickening’s links to poorer thinking and 64-91% for brain-vessel amyloid buildup
The catchAlzheimer’s changes could precede vascular damage, reversing the assumed mediation pathway