Papers on KRAS mutation

15 papers

Tuesday, August 11

medRxivAug 11

Classical driver mutations are not associated with metachronous lesion risk in patients undergoing post-polypectomy surveillance following removal of conventional adenomas in a bowel screening setting

Preprint: cohort study of 723 peopleBiomarkers

Paper

Friday, January 9

Critical Reviews in Oncology/hematologyJan 9

Why isn't an oncogenic mutation in KRAS enough to induce and sustain transformation?

ReviewMechanisms

Paper

Tuesday, December 30

CancersDec 30

Age-Related Multigene Analysis of Colorectal Cancer Using Next-Generation Sequencing

Cross-sectional study of 54 peopleMechanisms

Paper

Wednesday, October 29

EBioMedicineOct 29

AI-derived body composition analysis reveals muscle volume and metformin-associated adipose effects and the obesity paradox in non-small cell lung cancer

Cohort study of 1,275 peopleNon-small cell lung cancer

Paper

Thursday, September 25

Cancer Epidemiology, Biomarkers & PreventionSep 25

Pan-Cancer Analyses Reveal Disparities in Tumor Genomic Profiles by Race/Ethnicity, Age, and Sex

Cross-sectional study of 104,399 peopleMechanisms

Paper

Thursday, June 26

DiagnosticsJun 26

Eosinophilic Cells as a Distinct Morphological Feature in BRAFV600E-Mutated Ovarian Serous Borderline Tumors

Cross-sectional study of 63 peopleBiomarkers

Paper

Monday, April 15

bioRxivApr 15

APOBEC shapes tumor evolution and age at onset of lung cancer in smokers

Preprint: cross-sectional study of 309 peopleLung

Paper

Tuesday, November 23

Frontiers in OncologyNov 23

TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer

Experiments in human cellsCellular senescence

Paper

Saturday, May 30

Cancer Epidemiology, Biomarkers & PreventionMay 30

Comparison of Tissue-Based Molecular Markers in Younger versus Older Patients with Colorectal Neoplasia

Case-control study of 211 peopleColorectal neoplasia

Paper

Monday, May 11

Nature CommunicationsMay 11

Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers

Experiments in animalsVitamin C

Paper

Thursday, December 6

Journal of Experimental & Clinical Cancer ResearchDec 6

Co-occurring KRAS mutation/LKB1 loss in non-small cell lung cancer cells results in enhanced metabolic activity susceptible to caloric restriction: an in vitro integrated multilevel approach

Experiments in human cellsOxidative phosphorylation

Paper

Thursday, November 1

Scientific ReportsNov 1

Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice

Experiments in miceKRAS

Paper

Wednesday, September 26

Environmental and Molecular MutagenesisSep 26

Lifespan Kras mutation levels in lung and liver of B6C3F₁ mice

Experiments in miceBiomarkers

Paper

Thursday, September 28

Cellular and Molecular Gastroenterology and HepatologySep 28

Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis

Experiments in miceApoptosis

Paper

Thursday, February 9

CancerFeb 9

Unique prevalence of oncogenic genetic alterations in young patients with lung adenocarcinoma

Cohort study of 1,746 peopleLung

Paper