IRS-2 pool level

1 paper1 finding

Animals1

Upstream

1

POU1F1

downin mice1

1 study

POU1F1 decreases IRS-2 pool level in mice.
“These include a decreased IRS-2 pool level, a decrease in PI3K activity and its association with IRS-2 and decreased docking of p85alpha to IRS-2.”
Animalsin aged Snell dwarf mice
Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm
Mechanisms of ageing and development1 May 2002

Latest

Mechanisms of Ageing and Development1 May

Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm

Experiments in micePI3K–AKT signalling