Intrinsic capacity index
2 papers4 findings
- Humans2
Upstream
2Prolonged multimorbidity
downin humans1
1 study
Prolonged multimorbidity
downin humans1
prolonged multimorbidity decreases intrinsic capacity index in humans (β = -0.0712, p < 0.01).
“prolonged multimorbidity (β = -0.0712, p < 0.01) was more detrimental than onset alone (β = −0.0368, p < 0.01).”
Humanspersistence model
Research Square25 Aug 2026Preprint
Multimorbidity shock
downin humans1
1 study
Multimorbidity shock
downin humans1
multimorbidity shock decreases intrinsic capacity index in humans (β = -0.0245, p < 0.05).
“When individual fixed effects and dynamic correction were added, the naïve cross-sectional link between multimorbidity shock and IC was positive (β = 0.357, p < 0.01), but the sign flipped (β = -0.0245, p < 0.05)”
Humansin dynamic fixed-effects model
Research Square25 Aug 2026Preprint
Associations
2Measurement reliability
upin humans1
1 study
Measurement reliability
upin humans1
Intrinsic capacity index is associated with measurement reliability in humans (CR or hierarchical omega ≥0.7; average variance extracted ≥0.5).
“All five IC domains and the general IC factor fulfilled reliability thresholds”
Humansgeneral intrinsic capacity factor and all five domainsself-administered web-based assessment52.4% womensn = 6,434
Annals of geriatric medicine and research3 Sep 2025
Construct validity
upin humans1
1 study
Construct validity
upin humans1
Intrinsic capacity index is associated with construct validity in humans (CFI reported as CLI=0.947; TLI=0.938; RMSEA=0.089; SRMR=0.051).
“CFA demonstrated construct validity for the second-order factor structure with acceptable overall model fit”
HumansSingapore Life Panel respondentsself-administered web-based assessment52.4% womensn = 6,434
Annals of geriatric medicine and research3 Sep 2025