Intratumoral senescent CD8+ T cell frequency

Biomarker

1 paper2 findings

  • Humans1

Associations

1

Age

upin humans1upin mice1

1 study
  1. Age is associated with intratumoral senescent CD8+ T cell frequency in mice.

    “Single-cell profiling of human and mouse cancer tissues reveals that the frequency of intratumoral senescent CD8+ T cells increases with age”

    Animalscancercancer tissue

    An age-related decrease in leptin contributes to CD8⁺ T cell aging in the tumor microenvironment

    Cell reports. Medicine25 Aug 2025

  2. Age is associated with intratumoral senescent CD8+ T cell frequency in humans.

    “Single-cell profiling of human and mouse cancer tissues reveals that the frequency of intratumoral senescent CD8+ T cells increases with age”

    Humanscancercancer tissue

    An age-related decrease in leptin contributes to CD8⁺ T cell aging in the tumor microenvironment

    Cell reports. Medicine25 Aug 2025

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