Intracellular iron accumulation

1. Caloric restriction prevents intracellular iron accumulation in yeast cells.

   “intracellular iron accumulated during aging but was prevented by CR and Ssd1 overexpression.”

   CellsDuring aging

   Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

   eLife·12 Jan 2026

2. Caloric restriction prevents intracellular iron accumulation in yeast cells.

   “intracellular iron accumulated during aging but was prevented by CR and Ssd1 overexpression.”

   Cellsduring aging

   Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

   eLife·13 Oct 2025Preprint

More on Caloric restriction

1. SSD1 prevents intracellular iron accumulation in yeast cells.

   “intracellular iron accumulated during aging but was prevented by CR and Ssd1 overexpression.”

   CellsSSD1 overexpression during aging

   Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

   eLife·12 Jan 2026

2. SSD1 prevents intracellular iron accumulation in yeast cells.

   “intracellular iron accumulated during aging but was prevented by CR and Ssd1 overexpression.”

   CellsSSD1 overexpression during aging

   Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

   eLife·13 Oct 2025Preprint

More on SSD1