Intracellular amino acid abundance

1. MDM1 increases intracellular amino acid abundance in yeast cells.

   “loss of Mdm1 causes persistent retention of Mup1 at the plasma membrane (PM), accompanied by reduced intracellular methionine and broad amino acid depletion.”

   CellsShown by MDM1 deletion during starvation

   Sphingolipid regulation by yeast Mdm1 supports adaptive remodeling of the methionine transporter Mup1

   Molecular biology of the cell·27 May 2026

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