Intermuscular adipose tissue area

There are 5 papers on intermuscular adipose tissue area in aging research: 1 trial and 4 observational studies in people.

Biomarker

5 papers study it2 more mention it3 findings

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“normal attenuation muscle area (β = -0.907, p = .019) and 10-year risk of atherosclerotic cardiovascular disease (β = 0.976, p = .002).”
Moderate resistance training reduces intermuscular adipose tissue and risk factors of atherosclerotic cardiovascular disease for elderly patients with type 2 diabetesDiabetes, obesity & metabolism2024doi:10.1111/dom.15684
  • Human trial1
  • Humans4

Interventions

1

Resistance training

downin humans1

1 study
  1. Resistance training decreases intermuscular adipose tissue area in humans (type 2 diabetes) (-0.512 ± 0.115 cm2 (-9.89%) vs +0.587 ± 0.115 cm2 (+10.34%) in control).

    “The IMAT area (measured by a computed tomography scan) in the resistance group decreased from 5.176 ± 1.249 cm2 to 4.660 ± 1.147 cm2”

    Human trialtype 2 diabetesskeletal muscle6 months

    Moderate resistance training reduces intermuscular adipose tissue and risk factors of atherosclerotic cardiovascular disease for elderly patients with type 2 diabetes

    Diabetes, obesity & metabolism

More on Resistance training

Associations

2

Mortality

downin humans1HR 0.79

1 study
  1. Intermuscular adipose tissue area predicts mortality in humans after curative-intent colon cancer surgery (HR 0.79 (95% CI 0.67-0.93)).

    “Patients with larger differences (Δ) of IMAT area and IMATI at 12 months, HR 0.79 (95% CI 0.67-0.93) and 0.49 (95% CI 0.30-0.80), respectively, had a lower mortality.”

    Humansafter curative-intent colon cancer surgery12 monthsn = 102

    Long-Term Evolution of Skeletal Muscle Quantity and Quality After Curative-Intent Colon Cancer Surgery: A Retrospective Cohort Study

    Diagnostics (Basel, Switzerland)

10-year risk of atherosclerotic cardiovascular disease

upin humans1

1 study
  1. Intermuscular adipose tissue area is associated with 10-year risk of atherosclerotic cardiovascular disease in humans (type 2 diabetes) (β = 0.976, p = .002).

    “normal attenuation muscle area (β = -0.907, p = .019) and 10-year risk of atherosclerotic cardiovascular disease (β = 0.976, p = .002).”

    Human trialtype 2 diabetes

    Moderate resistance training reduces intermuscular adipose tissue and risk factors of atherosclerotic cardiovascular disease for elderly patients with type 2 diabetes

    Diabetes, obesity & metabolism

More on 10-year risk of atherosclerotic cardiovascular disease

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