Intermediate-density coronary calcium volume

1. Statins are associated with intermediate-density coronary calcium volume in humans (β = 0.89, SE = 0.39).

   “Statin treatment was associated with greater progression in intermediate-density (β = 0.89, SE = 0.39; P = 0.02)”

   Human trialPost hoc analysis of asymptomatic, statin-naive, intermediate-risk individualscoronary plaque3 years57.1% mensn = 338

   Calcium Density as a Marker of Coronary Plaque Stabilization in Primary Prevention: The CAUGHT-CAD Trial

   JACC. Cardiovascular imaging·15 Oct 2026

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