Immunoglobulin g
Effects
3Dermal atrophy
upin mice1
1 study
Dermal atrophy
upin mice1
Immunoglobulin g increases dermal atrophy in mice.
“IgG accumulates in the dermis with age and promotes dermal inflammation and atrophy.”
Animalsdermis
Aging-related IgG accumulation promotes skin inflammation
The Journal of investigative dermatology9 Sep 2026
Dermal inflammation
upin mice1
1 study
Dermal inflammation
upin mice1
Immunoglobulin g increases dermal inflammation in mice.
“IgG accumulates in the dermis with age and promotes dermal inflammation and atrophy.”
Animalsdermis
Aging-related IgG accumulation promotes skin inflammation
The Journal of investigative dermatology9 Sep 2026
Metabolic dysfunction
upin reviews1
1 study
Metabolic dysfunction
upin reviews1
Immunoglobulin g increases metabolic dysfunction.
“Experimental studies demonstrate that IgG accumulation in adipose tissue contributes to metabolic dysfunction via Neonatal Fc Receptor (FcRn)-dependent pathways.”
Reviewin adipose tissue
Immunoglobulin G and Aging: Biological Functions and Its Crosstalk with the Gut Microbiota
Rejuvenation research22 Nov 2025
Funding
1 grant since 2025National Institute of Allergy and Infectious DiseasesUS$444.1k
Latest
11 in 12 monthsFrontiers in Public Health
COVID-19 vaccination in relation to immune response and physical activity levels
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Alzheimer's & Dementia
Genetic evidence suggests a protective role of immunoglobulin M in Alzheimer's disease
Mendelian randomisation in peopleMechanisms
Nature Biomedical Engineering
Orthotopic liver xenotransplantation from gene-modified pig to decedent human
Case reportInterventions
The Journal of Investigative Dermatology
Aging-related IgG accumulation promotes skin inflammation
Experiments in miceInflammation
American Journal of Physiology Endocrinology and Metabolism
Mechanistic drivers of thermogenic adipose tissue dysfunction in aging and obesity
ReviewMechanisms
GSA 2025 Abstract
Mediating Role of CMV Infection and GrimAge in the Association of Education With Health Outcomes in Cancer Survivors
Cohort study of 1,337 peopleCancer
GSA 2025 Abstract
Cytomegalovirus, midlife inflammation, and subclinical cardiovascular disease: the SWAN Study
Cohort study of 100 peopleCardiovascular disease
Frontiers in Immunology
Temporal dynamics of IgG-mediated immunometabolic dysfunction: from acute obesity to chronic aging
ReviewMechanisms
International Journal of Molecular Sciences
Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data
Computational studyMechanisms