IL-22

5 papers2 findings

Humans3
Animals1

Interventions

1

Vitamin D

downin reviews1

1 study

Vitamin D decreases IL-22.
“vitamin D directly suppresses IL-22 through repressive VDREs independent aryl-hydrocarbon receptor (AhR) signalling”
Review
Immunometabolic control of cytokine production by micronutrients in health, aging, and inflammation
Frontiers in immunology5 May 2026

More on Vitamin D

Associations

1

Follow-up time

downin humans1

1 study

follow-up time is associated with IL-22 in humans.
“In this longitudinal study, we found that IL-22 levels decreased over time while ferritin levels increased over time.”
HumansAfrican American and White participants; three measurement time pointsmen and womens
Longitudinal analysis of cytokines, chemokines, and inflammatory markers in a middle-aged cohort
GeroScience22 May 2026

Latest

8 in 12 months

Frontiers in Immunology9 Sep

Thymic regeneration and tumor immunotherapy

ReviewBlood and immune system

GeroScience23 May

Longitudinal analysis of cytokines, chemokines, and inflammatory markers in a middle-aged cohort

Cohort study in peopleInflammation

Frontiers in Immunology21 May

Immunometabolic control of cytokine production by micronutrients in health, aging, and inflammation

ReviewInflammation

Acta Dermato-venereologica19 May

Comprehensive Transcriptomic Profiling of Nonatopic Prurigo Nodularis in Korean Patients Reveals Il-22-driven Epidermal Stress and Neuro-immuno-fibrotic Remodelling

Case-control study in peopleExtracellular matrix remodelling

Tzu Chi Medical Journal14 May

Adaptive immune crosstalk and complement dysregulation in the aging retina

ReviewComplement system

Molecular Therapy1 Mar

Lipidated interleukin-22 reduces body weight and spares lean mass in mice by a novel gut-acting mechanism additive to GLP-1 agonism

Experiments in miceGut and microbiome

AAIC 2025 Abstract9 Jan

Correlation Between Plasma Biomarkers Identified in Normal, SCD, and MCI subjects, with PET Amyloid and Tau Neuroimaging

Cross-sectional study of 163 peopleBiomarkers

Immunity & Ageing28 Dec

Activation of aryl hydrocarbon receptor signaling by indole-3-lactic acid from Bacillus velezensis DS2 reinforces gut mucosal immunity and attenuates inflammaging in aged mice

Experiments in miceGut and microbiome

Biomedicine & Pharmacotherapy19 Dec

Human artificial chromosome carrying R-spondin1 and IL-22 expression cassettes in rejuvenated MSCs enhances therapeutic efficacy in ulcerative colitis model mice

Experiments in animalsInterventions

Nature Communications30 May

Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis

Experiments in animalsMechanisms