IGFBP3

3 papers1 finding

Humans1
Animals1
Cells1

Interventions

1

HTRA4

upin human cells1

1 study

HTRA4 increases IGFBP3 in human cells.
“IGFBP-3 protein was also significantly elevated in the media of HtrA4-treated HUVECs.”
Cellsin media of HUVECs
Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes
Placenta14 Dec 2019

Funding

1 grant since 2023

National Heart, Lung, and Blood InstituteUS$480.6k

Role of IGFBP3 in Neonatal Heart Regeneration
National Heart, Lung, and Blood InstituteColumbia University Health SciencesUS$135k2022–2026

Latest

3 in 12 months

Research Square22 Sep

Identification of Cellular Senescence-Related Hub Genes and Their Association with Immune Infiltration in Abdominal Aortic Aneurysm: A Comprehensive Bioinformatics Analysis

Preprint: computational studyAbdominal aortic aneurysm

GeroScience8 Aug

DNA methylation signatures in skeletal muscle associated with physical function in healthy older adults

Cohort study of 92 peopleDNA methylation

AAIC 2025 Abstract25 Dec

Plasma proteomic profiles mediate and modulate the association between healthy lifestyles and dementia

Study in peopleBiomarkers

Placenta14 Dec

Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes

Experiments in human cellsCellular senescence

Nature Medicine1 Jul

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

Experiments in miceBones and joints

The Lancet Oncology14 May

Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

Study in peopleIGF-1

Endocrinology1 Sep

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

Experiments in miceGrowth hormone axis