IGF1R and AKT phosphorylation
1 paper1 finding
- Cells1
Upstream
1IGF1R
downin mouse cells1
1 study
IGF1R
downin mouse cells1
IGF1R decreases IGF1R and AKT phosphorylation in mouse cells.
“MEFs expressing the human longevity-associated IGF1R mutations attenuated IGF1 signaling, as demonstrated by significant reduction in phosphorylation of both IGF1R and AKT after IGF1 treatment”
Cellsin Igf1r null MEFs expressing human IGF1R variants after IGF1 treatment
Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles
Aging cell12 Apr 2011
Latest
Aging Cell
Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles
Experiments in mouse cellsPI3K–AKT signalling