I3 score

I3 score predicts mortality in humans (HR 2.42, 95% CI 1.74–3.37).

“Higher I3 scores were independently associated with increased mortality (hazard ratio [HR] 2.42, 95% CI 1.74–3.37 for high vs. low scores)”

Humans10-yearn = 1,009

Association of an inflammaging score based on IL-6, IL-10 and CXCL9, and frailty with long-term mortality in hospitalized older adults

Immunity & ageing : I & A·19 Dec 2025