Hydrogen sulphide production

Biomarker

1 paper3 findings

  • Animals1

Interventions

1

Dietary restriction

downin mice1upin mice1

1 study
  1. Dietary restriction decreases hydrogen sulphide production in mice.

    “Strain TejJ48 (no reported lifespan effect following 40% DR) exhibited significantly reduced hepatic H2S production”

    Animalsin TejJ48 recombinant inbred miceliver10 monthsfemales

    Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

    GeroScience11 Mar 2020

  2. Dietary restriction increases hydrogen sulphide production in mice.

    “Following long-term (10 months) 40% DR, strain TejJ89-reported to show lifespan extension under DR-exhibited elevated hepatic H2S production relative to its strain-specific ad libitum (AL) control.”

    Animalsin TejJ89 recombinant inbred miceliver10 monthsfemales

    Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

    GeroScience11 Mar 2020

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Associations

1

MPST

upin mice1

1 study
  1. Hydrogen sulphide production is associated with MPST in mice.

    “Increased hepatic H2S production in TejJ89 mice was associated with elevation of the mitochondrial H2S-producing enzyme 3-mercaptopyruvate sulfurtransferase (MPST).”

    Animalsin TejJ89 mice under 40% DRliverfemales

    Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

    GeroScience11 Mar 2020

More on MPST

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