Papers on HMG-CoA
99 papers5 new in 30 days
Thursday, October 9
Sunday, August 17
Life Sciences
Exercise improves aging-induced cardiac dysfunction and prolongs lifespan via Hmgcr
Experiments in fliesExercise
Sunday, March 30
Atherosclerosis
Simvastatin ameliorates senescence-induced mitochondrial dysfunction in vascular smooth muscle cells
Experiments in cellsSimvastatin
Wednesday, March 26
Biomedicine & Pharmacotherapy
Rosuvastatin restores liver tissue-resident NK cell activation in aged mice by improving mitochondrial function
Experiments in miceRosuvastatin
Tuesday, January 21
Monday, October 28
The Biochemical Journal
Mitigating neuroinflammation in cognitive areas: exploring the impact of HMG-CoA reductase inhibitor
Experiments in ratsStatins
Friday, September 13
Journal of Alzheimer's Disease
Association Between Statin Use and Dementia, and Related Mechanisms: A Bibliometric Analysis from 2007 to 2023
ReviewStatins
Thursday, September 12
Sunday, April 28
Metabolism
Statin treatment reduces leucine turnover, but does not affect endogenous production of beta-hydroxy-beta-methylbutyrate (HMB)
Non-randomized trial in 12 peopleStatins
Tuesday, January 16
bioRxiv
Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis
Preprint: experiments in human cellsMechanisms
Thursday, September 28
Diagnostic Pathology
Effect and mechanism of HMG-CoA reductase inhibitor on the improvement of elderly essential hypertension-induced vascular endothelial function impairment based on the JAK/STAT pathway
Randomized trial in 86 peopleStatins
Friday, September 15
Current Pharmaceutical Design
Statin as Repurposed Drug in Ovarian Cancer: A Comprehensive Review
ReviewStatins
Sunday, August 6
Friday, July 14
Wednesday, December 28
Saturday, December 24
International Journal of Molecular Sciences
Statins Show Anti-Atherosclerotic Effects by Improving Endothelial Cell Function in a Kawasaki Disease-like Vasculitis Mouse Model
Experiments in miceStatins
Wednesday, December 14
Research Square
3-Hydroxy-3-methylglutaryl (HMG)-coenzyme A (CoA) reductase inhibitor modulates biomarkers related to Alzheimer's disease pathology in a sepsis-surviving rat model
Preprint: experiments in ratsStatins
Friday, October 28
Nutrients
Statin-Induced Geranylgeranyl Pyrophosphate Depletion Promotes Ferroptosis-Related Senescence in Adipose Tissue
Experiments in mouse cellsFerroptosis
Sunday, September 18
Alzheimer's Research & Therapy
Cumulative effect of simvastatin, L-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimer's disease
Non-randomized trial in 10 peopleSimvastatin
Thursday, July 28
International Journal of Molecular Sciences
Neuroprotective Effects of Resveratrol by Modifying Cholesterol Metabolism and Aβ Processing in SAMP8 Mice
Experiments in miceResveratrol
Saturday, May 28
Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
Use of Statins and Hip Fracture Risk: a Case-Control Study
Case-control study in peopleHip fracture
Wednesday, May 4
European Review for Medical and Pharmacological Sciences
Examining the effects of HMG-CoA reductase inhibitors on anabolic and catabolic signaling pathway proteins associated with degenerative disc disease
Experiments in human cellsStatins
Saturday, December 18
Sunday, November 28
International Journal of Molecular Sciences
A Possible Role for HMG-CoA Reductase Inhibitors and Its Association with HMGCR Genetic Variation in Parkinson's Disease
ReviewStatins
Wednesday, August 11
Oxidative Medicine and Cellular Longevity
Implications on the Therapeutic Potential of Statins via Modulation of Autophagy
ReviewStatins
Sunday, August 8
Sunday, March 7
Acta Biochimica et Biophysica Sinica
Atorvastatin attenuates surgery-induced BBB disruption and cognitive impairment partly by suppressing NF-κB pathway and NLRP3 inflammasome activation in aged mice
Experiments in miceAtorvastatin
Sunday, January 24
European Journal of Pharmacology
Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice
Experiments in miceInterventions