CNS & Neurological Disorders Drug Targets·Jul 22The Role of Statins in the Management of Delirium: Recent AdvancesReviewStatinsPaper
Journal of the American Medical Directors Association·Jul 18The Effects of ARBs, ACEis, and Statins on Clinical Outcomes of COVID-19 Infection Among Nursing Home ResidentsCohort study of 154 peopleCOVID-19Paper
Cell Death Discovery·Apr 8Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/STAT3 pathwayExperiments in miceAtorvastatinPaper
Aging and Disease·Feb 6Statins Induce a DAF-16/Foxo-dependent Longevity Phenotype via JNK-1 through Mevalonate Depletion in C. elegansExperiments in wormsStatinsPaper
Ageing Research Reviews·Feb 2Effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ageing: Molecular mechanismsReviewStatinsPaper
The Journal of Physiology·Aug 10Chronic statin therapy is associated with enhanced cutaneous vascular responsiveness to sympathetic outflow during passive heat stressCross-sectional study of 13 peopleStatinsPaper
Aging·May 12Modulation of Coenzyme Q₁₀ content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated agingExperiments in human cellsStatinsPaper
Neurochemical Research·Feb 28Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 ActivationExperiments in 60 miceAtorvastatinPaper
Canadian Journal of Physiology and Pharmacology·Feb 20Short telomere subtelomeric hypomethylation is associated with telomere attrition in elderly diabetic patients ¹Case-control study in peopleTelomerase and telomere maintenancePaper
Women & Health·Feb 6Lower femoral neck bone mineral density (BMD) in elderly women not on statinsCross-sectional study of 185 peopleBones and jointsPaper
Journal of Neurosciences in Rural Practice·Oct 3The Effect of Statins in Epilepsy: A Systematic ReviewSystematic reviewStatinsPaper
Molecular Cancer Therapeutics·Oct 17HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor IrradiationExperiments in miceStatinsPaper
Journal of Physiology and Pharmacology·Aug 19The role of mTOR inhibitors and HMG-CoA reductase inhibitors on young and old endothelial cell functions, critical for re-endothelialisation after percutaneous coronary intervention: an in vitro studyExperiments in human cellsmTOR inhibitorsPaper
bioRxiv·Jul 30Exploring repositioning opportunities and side-effects of statins: a Mendelian randomization study of HMG-CoA reductase inhibition with 55 complex traitsPreprint: Mendelian randomization in peopleStatinsPaper
Medical Hypotheses·May 17LDL-C levels in older people: Cholesterol homeostasis and the free radical theory of ageing convergeCommentaryMechanismsPaper
PNAS·May 14Combined HMG-COA reductase and prenylation inhibition in treatment of CCMExperiments in miceStatinsPaper
BMC Complementary and Alternative Medicine·Feb 12Medication use by middle-aged and older participants of an exercise study: results from the Brain in Motion studyStudy in peoplePopulationsPaper
Ceska a Slovenska Farmacie·Jul 1The evaluation of the prevalence of constipation at the Centre of clinical gerontologyStudy in peoplePopulationsPaper
The Journals of Gerontology, Series A·Mar 19Effect of Statin Use on Mobility Disability and its Prevention in At-risk Older Adults: The LIFE StudyRandomized trial in 1,635 peopleStatinsPaper
Journal of the American Association of Nurse Practitioners·Jul 12Statins' effect on plasma levels of Coenzyme Q10 and improvement in myopathy with supplementationSystematic reviewStatinsPaper
Expert Review of Cardiovascular Therapy·Oct 1CoQ10 and L-carnitine for statin myalgia?ReviewStatinsPaper
PLOS One·Jun 21Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylationExperiments in fliesStatinsPaper
Aging·Dec 1Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA)Experiments in miceStatinsPaper
Atherosclerosis·Aug 6Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind studyRandomized trial in 25 peopleCoenzyme Q10Paper
Mitochondrion·Mar 27Coenzyme Q10 and statins: biochemical and clinical implicationsReviewStatinsPaper
The Annals of Pharmacotherapy·Jan 31Considerations for supplementing with coenzyme Q10 during statin therapySystematic reviewStatinsPaper
Drug Safety·Jan 1Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trialRandomized trial in 72 peopleSimvastatinPaper