HLA-DR+ CD4+ T cells

Biomarker

1 paper studies it3 more mention it2 findings

  • Humans1

Associations

2

White matter hyperintensities

downin humans1

1 study
  1. White matter hyperintensities are associated with HLA-DR+ CD4+ T cells in humans.

    “the percentage of HLA-DR+ T4 cells was lower in volunteers with periventricular and deep WMH”

    Humanscontrolled HIV-1 infectionperipheral blood

    Low levels of peripheral blood activated and senescent T cells characterize people with HIV-1-associated neurocognitive disorders

    Frontiers in immunology

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Neurocognitive impairment

downin humans1

1 study
  1. Neurocognitive impairment is associated with HLA-DR+ CD4+ T cells in humans.

    “activated (HLA-DR+) as well as senescent (CD57+CD28-CD27±) T4 cells and T8 cells were less prevalent in the peripheral blood of participants with NCI than in participants without the disorder”

    Humanscontrolled HIV-1 infectionperipheral bloodn = 65

    Low levels of peripheral blood activated and senescent T cells characterize people with HIV-1-associated neurocognitive disorders

    Frontiers in immunology

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