GrimEAA

1. GrimEAA mediates forced vital capacity in humans.

   “For former smokers, a long time since smoking cessation had a positive indirect impact on FVC through GrimEAA”

   Humansindirect effect in former smokersn = 2,474

   Epigenetic age acceleration mediates the association between smoking and diabetes-related outcomes

   Clinical epigenetics·3 Jun 2023

1. GrimEAA mediates diabetes-related outcomes in humans.

   “second-generation epigenetic clocks (GrimEAA, DunedinPACE, and PhenoEAA) significantly mediated the associations between smoking and diabetes-related outcomes”

   Humansmediation analysisn = 2,474

   Epigenetic age acceleration mediates the association between smoking and diabetes-related outcomes

   Clinical epigenetics·3 Jun 2023

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