GLB1 expression

1. Fisetin decreases GLB1 expression in humans.

   “At the primary endpoint, day 45, both fisetin dosing regimens significantly decreased galactosidase beta 1 (GLB1) and P16 INK4A (P16) gene expression.”

   Human trialBoth dosing regimensperipheral blood mononuclear cell100 mg/day or 20 mg/kg for two consecutive days on and 28 days off45 days

   Effects of Two Fisetin Dosing Regimens on Reducing Senescence-Related Genes in Peripheral Blood Mononuclear Cells in Aged Humans

   Preprints.org·22 Jul 2026Preprint

More on Fisetin