GGA-LET-7I

Ovarian aging is associated with GGA-LET-7I in chickens.

“gga-let-7i exhibited the highest abundance and showed progressive upregulation during aging.”

Animalsovaryfemales

miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway

Poultry science·28 Jan 2026