Gene expression variability

age-related differentially expressed genes are associated with gene expression variability in flies.

“both down- and upregulated genes within enriched functional categories show reduced expression variability and experience strong purifying selection.”

Model organismsdown- and upregulated genes within enriched functional categoriesfemales

The aging transcriptome: a condition-dependent response to a deteriorating soma

bioRxiv (Cold Spring Harbor Laboratory)·25 Dec 2025Preprint