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GDF11/8

Biomarker

4 papers study it2 more mention it3 findings

  • Humans1
  • Animals3

Associations

3

Dementia

downin humans1HR 0.66

1 study

  1. GDF11/8 predicts dementia in humans (HR = 0.66, p = 0.00148).

    “low dual-specific aptamer-detected GDF11/8 levels also predicted increased 8 year dementia risk (HR = 0.66, p = 0.00148)”

    Humans8 yearn = 4,110

    Activated GDF11/8 subforms predict cardiovascular events and mortality in humans

    Nature communications

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Mortality

downin humans1HR 0.33

1 study

  1. GDF11/8 predicts mortality in humans (HR = 0.33, p = 4.8 × 10−40).

    “all-cause mortality (HR = 0.33, p = 4.8 × 10−40)”

    Humanspatients at risk for future cardiovascular eventsn = 11,609

    Activated GDF11/8 subforms predict cardiovascular events and mortality in humans

    Nature communications

Cardiovascular events

downin humans1HR 0.43

1 study

  1. GDF11/8 predicts cardiovascular events in humans (HR = 0.43, p = 9.1 × 10−63).

    “low dual-specific aptamer-detected GDF11/8 levels strongly predicted adverse outcomes, including cardiovascular events (HR = 0.43, p = 9.1 × 10−63)”

    Humanspatients at risk for future cardiovascular eventsn = 11,609

    Activated GDF11/8 subforms predict cardiovascular events and mortality in humans

    Nature communications

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