GAP43

Biomarker2 papers1 finding

Humans1
Animals1

Associations

1

Fibrinogen

upin humans1

1 study

Fibrinogen is associated with GAP43 in humans.
“Higher CSF fibrinogen was significantly associated with elevated pTau, GAP43, NRGN, and SNAP25, independent of amyloid status.”
Humansindependent of amyloid statuscsfn = 70
Vascular plasticity and microglial mediators link blood‐brain barrier dysfunction to synaptic decline in cognitively typical aging independent of amyloid · AAIC 2025 abstract · 10 Jan 2026

Latest

6

International Journal of Molecular SciencesAnimals27 Aug

Neuroprotective Effects of Zinc Sulfate Against Type 2 Diabetes-Induced Encephalopathy in Aged Rats

bioRxivHumansPreprint27 Aug

CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer's disease

Complement system

AAIC 2025 AbstractHumans10 Jan

Vascular plasticity and microglial mediators link blood‐brain barrier dysfunction to synaptic decline in cognitively typical aging independent of amyloid

AAIC 2025 AbstractHumans9 Jan

Synapse Protein Signatures in Cerebrospinal Fluid and Plasma Predict Cognitive Maintenance vs Decline in Alzheimer's Disease

AAIC 2025 AbstractHumans26 Dec

A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease

AAIC 2025 AbstractHumans25 Dec

Relationship between complement protein levels and tau pathology in pre‐symptomatic Alzheimer's disease resembles patterns observed in MCI