FusionAge-derived biological age

Cardiorespiratory fitness predicts FusionAge-derived biological age in humans.

“We validated these findings in the National Health and Nutrition Examination Survey, confirming that cardiorespiratory fitness is a major, consistent driver of biological age.”

HumansValidated in the National Health and Nutrition Examination Survey

FusionAge framework for multimodal machine learning-based aging clocks uncovers cardiorespiratory fitness as a major driver of aging and inflammatory drivers of aging in response to spaceflight

medRxiv·1 Dec 2025Preprint

FusionAge-derived biological age is associated with mortality in humans.

“FusionAge-derived biological age is more strongly associated with incident disease and mortality compared to chronological age in UK Biobank individuals.”

HumansUK Biobank; stronger association than chronological age

FusionAge framework for multimodal machine learning-based aging clocks uncovers cardiorespiratory fitness as a major driver of aging and inflammatory drivers of aging in response to spaceflight

medRxiv·1 Dec 2025Preprint

FusionAge-derived biological age is associated with incident disease in humans.

“FusionAge-derived biological age is more strongly associated with incident disease and mortality compared to chronological age in UK Biobank individuals.”

HumansUK Biobank; stronger association than chronological age

FusionAge framework for multimodal machine learning-based aging clocks uncovers cardiorespiratory fitness as a major driver of aging and inflammatory drivers of aging in response to spaceflight

medRxiv·1 Dec 2025Preprint