Framingham General Cardiovascular Risk Score

Framingham General Cardiovascular Risk Score impairs cognitive function in humans (-0.010 SD/year, 95% CI -0.013, -0.008).

“A 10% increment in baseline FGCRS was associated with a faster decline in global cognition (-0.010 SD/year, 95% CI -0.013, -0.008).”

Humansn = 6,402

Association of baseline level of cardiovascular risk burden and its temporal changes with cognitive decline

Frontiers in aging neuroscience·Sep 1, 2022

Framingham General Cardiovascular Risk Score impairs pulmonary function in humans (β: -0.013, 95% CI: -0.023 to -0.003).

“the highest FGCRS was associated with faster PF decline (β: -0.013, 95% CI: -0.023 to -0.003) compared with the lowest FGCRS”

Humansup to 22 yearsn = 1,442

Influence of cardiovascular risk burden on pulmonary function trajectory: role of physical and social activities

Aging·Aug 4, 2022

Framingham General Cardiovascular Risk Score is associated with activities-of-daily-living disability in humans (OR = 1.023 (BADL), OR = 1.028 (IADL)).

“a positive correlation was identified between FGCRS and ADL disability (BADL: OR = 1.023, IADL: OR = 1.028)”

Humansn = 6,123

Relationship between Cardiovascular Risk and ADLs' Disability among Middle-aged and Older Adults in China: Evidence from a Longitudinal Study

Research Square·Apr 27, 2023Preprint

Framingham General Cardiovascular Risk Score is associated with cognitive function in humans.

“However, there was no consistent relationship between the direction of changes in FGCRS and cognitive decline.”

Humansn = 4,336

Association of baseline level of cardiovascular risk burden and its temporal changes with cognitive decline

Frontiers in aging neuroscience·Sep 1, 2022