What does the research say about fractional anisotropy and mean diffusivity?

Fractional anisotropy and mean diffusivity

There are 2 papers on fractional anisotropy and mean diffusivity in aging research: 2 observational studies in people. The newest story, Nov 1, 2026: “Brain injury linked to white matter differences in women”.

Biomarker

2 papers study it73 more mention it2 findings

1 new paper in 30 daysSee all 75 papers on fractional anisotropy and mean diffusivity

“in the fornix, for which the subcallosal gyrus thickness was significantly correlated to FA and MD (p < 0.05 FDR corrected).”

Age-related assessment of diffusion parameters in specific brain tracts correlated with cortical thinningNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020doi:10.1007/s10072-020-04688-9

Humans2

Interventions

Apoe ε4 status

no changein humans1

1 study

Apoe ε4 status was not clearly linked with fractional anisotropy and mean diffusivity in humans.
“APOE ε4 status was not predictive of either measure.”
Humanswhite mattern = 49
Tract Specificity of Age Effects on Diffusion Tensor Imaging Measures of White Matter Health
Frontiers in aging neuroscienceMar 15, 2021

Associations

Subcallosal gyrus thickness

mixedin humans1

1 study

Subcallosal gyrus thickness is associated with fractional anisotropy and mean diffusivity in humans (healthy individuals).
“in the fornix, for which the subcallosal gyrus thickness was significantly correlated to FA and MD (p < 0.05 FDR corrected).”
Humanshealthy individualsfornixn = 158
Age-related assessment of diffusion parameters in specific brain tracts correlated with cortical thinning
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologySep 4, 2020

Latest

13 papers in 12 months

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Study of 28 peopleResistance training

Paper

Women's HealthSep 3

Brain injury linked to white matter differences in women

A cross-sectional analysis of 363 women with recorded injuries and 10,128 controls linked brain scan differences to injury history and menopause timing.A cross-sectional analysis of 363 women with recorded injuries and 10,128 controls linked brain scan differences to injury history and menopause timing.

Cross-sectional studyPopulations