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Four-biomarker frailty model

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Survival

mixedin humans1

1 study

  1. Four-biomarker frailty model predicts survival in humans.

    “Moreover, frailty estimate obtained with this model led to a more refined prediction of survival on a 3-year follow-up.”

    HumansFrailty estimate from the four-biomarker model3 yearsn = 463

    The combination of GDF15, FGF21, sRAGE and NfL plasma levels can identify frailty in community-dwelling people across old age

    Mechanisms of ageing and development4 Jun 2025

Frailty status

mixedin humans1

1 study

  1. Four-biomarker frailty model predicts frailty status in humans (82% accuracy).

    “The model based on those four biomarkers estimated frailty with 82 % accuracy.”

    HumansRandom Forest Decision model using GDF15, FGF21, sRAGE and NfLplasman = 463

    The combination of GDF15, FGF21, sRAGE and NfL plasma levels can identify frailty in community-dwelling people across old age

    Mechanisms of ageing and development4 Jun 2025

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