What does the research say about Fatty infiltration?

Fatty infiltration

There are 7 papers on fatty infiltration in aging research: 5 observational studies in people, 2 reviews. The newest story, Oct 20, 2026: “Pretraining helps outline muscles in MRI scans with few labels”.

Biomarker

7 papers study it102 more mention it3 findings

3 new papers in 30 daysSee all 109

“high BMI with vitamin D deficiency/insufficiency group had a significantly increased risk of FI > grade 2 (OR = 10.69, p < 0.001)”

Vitamin D inadequacy combined with high BMI affects paraspinal muscle atrophy and pain intensity in postmenopausal womenClimacteric : the journal of the International Menopause Society2021doi:10.1080/13697137.2021.1990257

Humans5

Associations

Osteopenia

upin humans1

1 study

Osteopenia is associated with fatty infiltration in humans (relative to controls).
“FI demonstrated greater sensitivity across diagnostic comparisons, with significant increases observed in both osteopenia and osteo- porotic groups relative to controls”
Reviewrelative to controls
Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study
Frontiers in endocrinologyNov 25, 2025

Latest

29 papers in 12 months

HSS JournalMay 13

GLP-1 Agonist Use Is Not Associated With a Reduction of Paraspinal Muscle Quality in Diabetic Patients With Low Back Pain: A Retrospective Cohort Study

Cohort study of 128 peopleGLP-1 receptor agonists

Paper

Frontiers in EndocrinologyNov 25

Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study

Meta-analysis of observational studiesOsteoporosis

Paper

Clinical Spine SurgeryNov 4

The Impact of Paraspinal Sarcopenia Compared With Generalized Sarcopenia on Conservative Treatment Outcomes in Degenerative Lumbar Spinal Stenosis

Cohort study of 101 peopleSarcopenia

Paper

JSES InternationalOct 6

Sarcopenia of the deltoid as an indicator of outcome following reverse total shoulder arthroplasty: a systematic review and meta-analysis

Meta-analysis of observational studiesSarcopenia

Paper

The Spine JournalJul 8

Paraspinal sarcopenia independently predicts patient-reported outcomes following open but not minimally invasive single-level lumbar decompression

Cohort study of 152 peopleSarcopenia

Paper

DaruOct 25

Association between perioperative statin-ezetimibe therapy and reoperation following arthroscopic rotator cuff repair: A TriNetX database study

Cohort study of 1,114 peopleStatin + ezetimibe

Paper

Journal of Imaging Informatics in MedicineOct 20

Pretraining helps outline muscles in MRI scans with few labels

In an independent cohort, an outline-overlap score rose from 0.11 without adaptation to 0.61 after further training with four labeled subjects.In an independent cohort, an outline-overlap score rose from 0.11 without adaptation to 0.61 after further training with four labeled subjects.

Computational studyMuscle

Paper

Advanced ScienceOct 4

Intramuscular fat links to spinal muscle loss and weakness

People with intramuscular fat fractions above 10% showed significantly lower paraspinal muscle mass and strength than those with levels below 5%.People with intramuscular fat fractions above 10% showed significantly lower paraspinal muscle mass and strength than those with levels below 5%.

Cross-sectional study in peopleMuscle

Paper

Frontiers in ImmunologySep 19