Fat-free muscle volume

1. Abdominal aortic calcification is associated with fat-free muscle volume in humans (OR 2.52, 95% CI 1.88-3.38).

   “Individuals with moderate and high, compared to low ML-AAC24, had greater odds for low FFMV (1.58, 95%CI: 1.28-1.95 and 2.52, 95%CI: 1.88-3.38, respectively)”

   Humansn = 33,640

   Automated abdominal aortic calcification, muscle health and incident falls: the UK Biobank Imaging Study

   Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·21 May 2026

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1. Creatinine-to-cystatin C ratio predicts fat-free muscle volume in humans (AUC 0.577-0.609 men, 0.622-0.722 women).

   “creatinine to cystatin C showed poor to acceptable diagnostic power for identifying low fat-free muscle volume”

   Humansfully adjusted modelsn = 12,873

   Diagnostic Power of Serum Creatinine/Cystatin C Ratio for Identifying Low MRI-Muscle Volume and Low Grip Strength: Data From 9 731 to 149 707 UK Biobank Older Adults

   The journals of gerontology. Series A, Biological sciences and medical sciences·14 Nov 2024

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1. Telomere length is associated with fat-free muscle volume in humans (aβ = 0.017, 95% CI 0.009 to 0.026, P < 0.001).

   “In the fully adjusted model, thigh fat-free muscle volume was associated with LTL in the overall sample (adjusted standardized β (aβ) = 0.017, 95% CI 0.009 to 0.026, P < 0.001, per SD increase in LTL)”

   Humansthighn = 16,356

   Leukocyte telomere length is associated with MRI-thigh fat-free muscle volume: data from 16 356 UK Biobank adults

   Journal of cachexia, sarcopenia and muscle·29 Mar 2024

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