Abdominal aortic calcification

4 papers9 findings

Associations

Mortality

downin humans1upin humans1HR 0.79–1.99

1 study

Abdominal aortic calcification lowers the risk of mortality in humans (HR 0.79 (95% CI 0.62, 0.98)).
“Among patients 80+ years, elevated AAC was protective for mortality [HR 0.79 (95% CI 0.62, 0.98)].”
Humansstratified by age groupn = 1,219
EFFECT MODIFICATION OF AGE AND SEX BETWEEN AORTIC CALCIFICATION AND MORTALITY IN A COMMUNITY SAMPLE OF OLDER PATIENTS
GSA 2024 abstract31 Dec 2024
Abdominal aortic calcification raises the risk of mortality in humans (HR 1.99 (95% CI 1.66, 2.41)).
“Those with elevated AAC had 99% higher mortality hazard than those with unelevated AAC [HR 1.99 (95% CI 1.66, 2.41)].”
Humansadjusted for body mass index and Charlson Comorbidity Indexn = 6,647
EFFECT MODIFICATION OF AGE AND SEX BETWEEN AORTIC CALCIFICATION AND MORTALITY IN A COMMUNITY SAMPLE OF OLDER PATIENTS
GSA 2024 abstract31 Dec 2024

Frailty

upin humans1OR 1.27

1 study

Abdominal aortic calcification is associated with frailty in humans (OR 1.27, 95% CI 1.12-1.44).
“or frail (ORs 1.27 95%CI 1.12-1.44 moderate; 1.58 95%CI 1.31-1.91 high), adjusted for multiple covariates.”
Humansmoderate ML-AAC24 compared to low ML-AAC24n = 49,081
Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study
GeroScience23 Jun 2026

Pre-frailty

upin humans1OR 1.06

1 study

Abdominal aortic calcification is associated with pre-frailty in humans (OR 1.06, 95% CI 1.00-1.12).
“Compared to individuals with low ML-AAC24, those with moderate and high ML-AAC24 had greater odds of being pre-frail (ORs 1.06 95%CI 1.00-1.12 moderate;”
Humansmoderate ML-AAC24 compared to low ML-AAC24n = 49,081
Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study
GeroScience23 Jun 2026

Falls

upin humans1HR 1.31

1 study

Abdominal aortic calcification is associated with falls in humans (HR 1.31, 95% CI 1.02-1.68).
“Compared to low ML-AAC24, high ML-AAC24 was associated with greater hazards for an incident fall-related hospitalisation (1.31, 95%CI: 1.02-1.68).”
Humansn = 48,482
Automated abdominal aortic calcification, muscle health and incident falls: the UK Biobank Imaging Study
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research21 May 2026

Sarcopenia

upin humans1OR 1.69

1 study

Abdominal aortic calcification is associated with sarcopenia in humans (OR 1.69, 95% CI 1.24-2.29).
“and sarcopenia (1.40, 95%CI:1.12-1.76 and 1.69, 95%CI:1.24-2.29, respectively)”
Humansn = 35,834
Automated abdominal aortic calcification, muscle health and incident falls: the UK Biobank Imaging Study
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research21 May 2026