Extracellular fibronectin density

Dermal aging is associated with extracellular fibronectin density in human cells.

“we examined human dermal fibroblasts (HDF) from aged skin and observed that they produce lower extracellular FN densities in vitro than young HDFs.”

Cellscultured human dermal fibroblastsdermal fibroblast

Dysregulation of extracellular fibronectin and α5-integrin in dermal aging

Molecular biology of the cell·25 Jun 2025