Epicardial adipose tissue CT attenuation

1. Epicardial adipose tissue CT attenuation is associated with pericoronary adipose tissue CT attenuation in humans (β = 2.44 HU per SD).

   “ΔEAT attenuation was also associated with increasing PCAT attenuation (β = 2.44 HU per SD; P < 0.001)”

   Humansin exploratory analysespericoronary adipose tissuen = 313

   Serial Changes in Epicardial Adipose Tissue Attenuation Identify Residual Atherosclerotic Risk Independent of LDL Lowering: A Post Hoc Analysis of the CAUGHT-CAD Trial

   JACC. Cardiovascular imaging·8 Jul 2026

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1. Epicardial adipose tissue CT attenuation is associated with percent atheroma volume in humans (1.08% (95% CI: 0.47-1.69)).

   “and NCP percent atheroma volume by 1.08% (95% CI: 0.47-1.69; P < 0.001).”

   Humansin CAUGHT-CAD trial participants, adjusted for baseline plaque, treatment, and risk factor changescoronary arteryn = 313

   Serial Changes in Epicardial Adipose Tissue Attenuation Identify Residual Atherosclerotic Risk Independent of LDL Lowering: A Post Hoc Analysis of the CAUGHT-CAD Trial

   JACC. Cardiovascular imaging·8 Jul 2026

More on Percent atheroma volume

1. Epicardial adipose tissue CT attenuation is associated with fibrous plaque volume in humans (3.55 mm3 (95% CI: 0.67-6.43)).

   “fibrous plaque volume by 3.55 mm3 (95% CI: 0.67-6.43; P = 0.016)”

   Humansin CAUGHT-CAD trial participants, adjusted for baseline plaque, treatment, and risk factor changescoronary arteryn = 313

   Serial Changes in Epicardial Adipose Tissue Attenuation Identify Residual Atherosclerotic Risk Independent of LDL Lowering: A Post Hoc Analysis of the CAUGHT-CAD Trial

   JACC. Cardiovascular imaging·8 Jul 2026

More on Fibrous plaque volume

1. Epicardial adipose tissue CT attenuation is associated with noncalcified plaque volume in humans (4.21 mm3 (95% CI: 0.67-7.74)).

   “Per 1-SD increase in ΔEAT attenuation, NCP volume was higher by 4.21 mm3 (95% CI: 0.67-7.74; P = 0.020)”

   Humansin CAUGHT-CAD trial participants, adjusted for baseline plaque, treatment, and risk factor changescoronary arteryn = 313

   Serial Changes in Epicardial Adipose Tissue Attenuation Identify Residual Atherosclerotic Risk Independent of LDL Lowering: A Post Hoc Analysis of the CAUGHT-CAD Trial

   JACC. Cardiovascular imaging·8 Jul 2026

More on Noncalcified plaque volume