Atorvastatin
upin O. cuniculus1
Atorvastatin increases elastin in O. cuniculus (4.4% higher in treated group (p < 0.05)).
“percentage of elastin at 12 months, 4.4% lower in the control group compared to the treated group (p < 0.05).”
Animalsaorta2.5 mg/kg/daymales
Atherosclerosis26 May 2016
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$55.1kNational Institute of Child Health and Human DevelopmentUS$441.9k
Optimizing Minoxidil Delivery for Persistent Elastin Deposition in the Murine Vaginal Wall
National Institute of Child Health and Human DevelopmentWashington UniversityUS$441.9k2026–2028
2025 Elastin, Elastic Fibers and Microfibrils Gordon Research Conference and Gordon Research Seminar
National Institute of Arthritis and Musculoskeletal and Skin DiseasesGordon Research ConferencesUS$25k2025–2026
2023 Elastin, Elastic Fibers and Microfibrils Gordon Research Conference and Gordon Research Seminar
National Institute of Arthritis and Musculoskeletal and Skin DiseasesGordon Research ConferencesUS$30.1k2023–2024
In 17 human thoracic aorta samples, elastin stiffness, straightness, and lamellar length decreased significantly with age in males (p < 0.05) but not females.In 17 human thoracic aorta samples, elastin stiffness, straightness, and lamellar length decreased significantly with age in males (p < 0.05) but not females.
In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.