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medRxiv

Grip strength adds no clear value to midlife risk assessment

Adding grip strength changed scores for separating risk groups by minus 0.0046 and 0.0045 versus models including detailed body fat and muscle measurements.Adding grip strength changed scores for separating risk groups by minus 0.0046 and 0.0045 versus models including detailed body fat and muscle measurements.

Preprint: cross-sectional study of 616 peopleBiomarkers
Depression and Anxiety

Sleep-linked blood proteins associated with depression risk

Higher sleep-linked protein scores were associated with a lower depression rate during follow-up (hazard ratio 0.660); the abstract did not specify the comparison group.Higher sleep-linked protein scores were associated with a lower depression rate during follow-up (hazard ratio 0.660); the abstract did not specify the comparison group.

Cohort study of 36,852 peopleDepression
GeroScience

Biological aging and frailty linked to thinner central retinas

Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.

Cohort study of 45,542 peoplePopulations
Psychological Medicine

More functional deficits linked to depression and anxiety

Scores of four or more versus zero were linked to higher risks of depression and anxiety, with hazard ratios of 3.96 and 3.03, respectively.Scores of four or more versus zero were linked to higher risks of depression and anxiety, with hazard ratios of 3.96 and 3.03, respectively.

Cohort study of 212,033 peopleAnxiety