Double-negative T cells

2 papers1 finding

Humans1
Animals1

Upstream

1

Alzheimer's disease

upin mice1

1 study

Alzheimer's disease increases double-negative T cells in mice.
“At 15-18 months, AD mice exhibited elevated numbers of activated, highly differentiated DNTs, along with increased antigen-specific CD8+ and DNT cells relative to controls.”
Animalsin Tg(APPswe,PSEN1dE9)85Dbo/Mmjax AD micebrain
Antigen-Specifically Activated CD8+ and Double-Negative T Cells Accumulate in the Brain of Alzheimer's Disease Mice
Aging and disease27 Jun 2025

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