DNMT3A mutation
Biomarker1 paper
- In silico1
Latest
4International Journal of Molecular SciencesHumans
Donor TET2 variant linked to lower stem cell transplant survival
Recipients whose donors carried a TET2 Leu1721Trp variant lived a median of 14.3 months compared with 50.8 months for those with wild-type donors.Recipients whose donors carried a TET2 Leu1721Trp variant lived a median of 14.3 months compared with 50.8 months for those with wild-type donors.
bioRxivCellsPreprint
DNMT3A mutations enhance macrophage migration in cells
Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration…Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration toward injured tissue.