DNAm age measures

Biomarker

1 paper1 finding

Human trial1

Interventions

Mobile health exercise intervention

no changein humans1

1 study

Mobile health exercise intervention has no effect on DNAm age measures in humans.
“Accelerated GrimAge, accelerated PhenoAge, and DunedinPACE were stable from baseline to post-intervention.”
Human trialMyeloid malignancies receiving chemotherapy; single-arm comparison with baselineExercise program combined with a mobile application8–12 weeksn = 20
Exercise and epigenetic ages in older adults with myeloid malignancies
European journal of medical researchMay 30, 2023

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Blood methylation clocks capture two distinct biological domains of aging

Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle…Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.

Cohort study in peopleBiomarkers

Paper

medRxivMar 25