DNA methylation-based epigenetic clocks

Biomarker1 paper1 finding

  • Humans1

Associations

1

Brain aging estimates

mixedin humans1

1 study
  1. Brain aging estimates are associated with DNA methylation-based epigenetic clocks in humans.

    HumansDensely sampled participantfemalesn = 1

    Estimated brain-age gap rises by three years in pregnancy · Research square · 13 Aug 2026 · Preprint

Brain aging estimates →

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Research SquareHumansPreprint

Estimated brain-age gap rises by three years in pregnancy

Brain-age gap estimates rose by about three years during pregnancy and fell below pre-conception levels by 16 months postpartum in a longitudinal…Brain-age gap estimates rose by about three years during pregnancy and fell below pre-conception levels by 16 months postpartum in a longitudinal study.

Journal of the National Cancer InstituteHuman trial

Exercise linked to slower epigenetic aging in breast cancer survivors

In a randomized trial of 124 breast cancer survivors, a 12-month exercise intervention slowed epigenetic aging measured by GrimAge2 and DNAmFitAge…In a randomized trial of 124 breast cancer survivors, a 12-month exercise intervention slowed epigenetic aging measured by GrimAge2 and DNAmFitAge compared to a wellness control.