ADAMTS2
Gene1 paper3 findingsHGNC 218NCBI Gene 9509Taxon 9606
- Cells1
Interventions
1Hydrogen peroxide
upin human cells1Very low certainty
1 study
Hydrogen peroxide
upin human cells1Very low certainty
Hydrogen peroxide increases ADAMTS2 in human cells.
CellsH2O2 treatment in CCD-18Co human colon fibroblasts
Integrative Multi-Omics and Machine Learning Reveal Senescent Fibroblast-Associated ADAMTS2 as a Critical Indicator of Intestinal Inflammation in IBD · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026
Effects
1Senescence-associated secretory phenotype (SASP)
upin human cells1
1 study
Senescence-associated secretory phenotype (SASP)
upin human cells1
ADAMTS2 increases senescence-associated secretory phenotype (SASP) in human cells.
Cellsshown by knockdown in H2O2-treated CCD-18Co cells
Integrative Multi-Omics and Machine Learning Reveal Senescent Fibroblast-Associated ADAMTS2 as a Critical Indicator of Intestinal Inflammation in IBD · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026
Associations
1Inflammatory bowel disease
upin humans1
1 study
Inflammatory bowel disease
upin humans1
Inflammatory bowel disease is associated with ADAMTS2 in humans.
Humansin patients relative to controls
Integrative Multi-Omics and Machine Learning Reveal Senescent Fibroblast-Associated ADAMTS2 as a Critical Indicator of Intestinal Inflammation in IBD · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026