Differentiation index

Biomarker

2 papers1 finding

  • Cells2

Interventions

1

Roxadustat

upin mouse cells1

1 study
  1. Roxadustat increases differentiation index in mouse cells (+1.7).

    “When differentiation was induced without drugs, pretreated aged SCs formed hypertrophic myotubes (differentiation index +1.7), exhibited higher ATP content (+1.54-fold)”

    Cellspretreated aged SCs differentiated without drugs

    The HIF-1α Pathway Regulates Satellite Cell Fate During Aging Through Histone Lactylation

    Aging cell1 Feb 2026

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bioRxiv

DNA-based model detects age-linked shifts in cells

In sorted cell populations, a machine-learning model found age-associated shifts in DNA marks towards a developmental family that includes connective-tissue cells.In sorted cell populations, a machine-learning model found age-associated shifts in DNA marks towards a developmental family that includes connective-tissue cells.

Preprint: experiments in cellsBiomarkers