Differentially expressed genes

Biomarker1 paper1 finding

  • Animals1

Interventions

1

Running

upin rats1Very low certainty

1 study
  1. Running induces differentially expressed genes in rats.

    Animalssoleus muscle

    Methylome-transcriptome integration reveals molecular signatures of intrinsic aerobic capacity in aged skeletal muscle · Journal of sport and health science · 17 Sep 2026

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bioRxivAnimalsPreprint

Voluntary running shows limited neuroprotection in mice

In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology…In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology or memory.

medRxivHuman trialPreprint

Exercise mitigates disuse atrophy by building muscle reserve

In women undergoing limb immobilization, prehabilitation increased quadriceps area by 6.7% before disuse, preserving more post-immobilization muscle…In women undergoing limb immobilization, prehabilitation increased quadriceps area by 6.7% before disuse, preserving more post-immobilization muscle despite identical 3.2% relative losses.