Papers on diastolic function

356 papers41 new in 30 days

Friday, September 5

bioRxivSep 5

N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival

Preprint: experiments in miceInterventions

Paper

Tuesday, September 2

Cell SignalingSep 2

The role of circulating anti-aging αKlotho in cardiac aging

CommentaryInterventions

Paper

Wednesday, August 27

TheranosticsAug 27

FBLN7 KO attenuates age-related cardiac fibrosis by promoting TGFBR3/ALK1/Smad1 signaling and inhibiting the profibrotic phenotypes of cardiac fibroblasts

Experiments in miceMyocardial fibrosis

Paper

Saturday, August 23

JACC AdvancesAug 23

Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults

Cohort study of 409 peoplePopulations

Paper

Friday, August 15

DiabetesAug 15

Activated Protein C Suppresses Cardiomyocyte Senescence in Diabetic Cardiomyopathy via PAR1/PAR3-P85-CaMKIIδ Axis

Experiments in miceDiabetic cardiomyopathy

Paper

Wednesday, August 13

The Journal of Cardiovascular AgingAug 13

Aging diastole - root cause for atrial fibrillation and heart failure with preserved ejection fraction

ReviewMechanisms

Paper

Tuesday, August 12

bioRxivAug 12

NAD⁺ Replenishment Mitigates Cardiomyocyte Senescence and Corrects Heart Failure with Preserved Ejection Fraction in Aged Mice

Preprint: experiments in miceHeart failure with preserved ejection fraction

Paper

Thursday, August 7

Physiological ReportsAug 7

Elimination of hepatocyte-derived DPP4 downregulates cardiac immune- and collagen-related genes but does not alter cardiac function in aged male mice

Experiments in miceImmune response

Paper

Wednesday, August 6

bioRxivAug 6

Molecular Mechanisms of Cardiomyocyte Aging

Preprint: experiments in miceMechanisms

Paper

Monday, July 28

Journal of Applied PhysiologyJul 28

Cardiac responses to environmental heat exposure in young and older adults

Study of 20 peopleMechanisms

Paper

Tuesday, July 15

Frontiers in Cardiovascular MedicineJul 15

Construction and validation of a nomogram model for cognitive impairment in heart failure patients

Cohort study of 320 peopleCognitive impairment

Paper

Saturday, July 5

European Review of Aging and Physical ActivityJul 5

Effects of two-year adapted physical exercise program and nutritional counselling on cardio-sarcopenia syndrome in older adults with low muscle function

Randomized trial in 100 peopleSarcopenia

Paper

Thursday, June 19

JACC Basic to Translational ScienceJun 19

Controlled Right Ventricular Pressure Overload Can Rescue Left Ventricular Dysfunction by Promoting Biventricular Adaptive Hypertrophy

Experiments in ratsLeft ventricular dysfunction

Paper

Tuesday, June 3

American Journal of Physiology Heart and Circulatory PhysiologyJun 3

Cardiac PAD2 expression and myocardial citrullination decline with age in female mice independent of estrogen

Experiments in miceMechanisms

Paper

Saturday, March 22

Experimental GerontologyMar 22

Age related gut microbiota regulates energy-related metabolism to influence natural aging phenotypes in the heart

Experiments in ratsInterventions

Paper

Sunday, March 16

GeroScienceMar 16

Salutary effects of transdermal curcumin on multiple indices of health span in rodent models of normal aging and hypertension

Experiments in ratsCurcumin

Paper

Thursday, March 13

Aging CellMar 13

The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

Experiments in miceElamipretide

Paper

Wednesday, March 12

GeroScienceMar 12

Long-term dietary allyl isothiocyanate, a TRPA1 agonist, ameliorates cardiac fibrosis and diastolic dysfunction in aged mice

Experiments in miceCardiac fibrosis

Paper

Wednesday, February 19

The Journal of PhysiologyFeb 19

Systolic and diastolic dysfunction is exacerbated by age and spinal cord injury in male and female mice with central nervous system serotonin deficiency

Experiments in miceMechanisms

Paper

Saturday, February 15

Experimental GerontologyFeb 15

Inhibition of 15-PGDH by SW033291 ameliorates age-related heart failure in mice

Experiments in miceHeart failure

Paper

Friday, February 7

American Journal of Physiology Heart and Circulatory PhysiologyFeb 7

Allostatic load and cardiometabolic health in a young adult South African population: the African-PREDICT study

Cohort study of 1,054 peopleBiomarkers

Paper

Saturday, January 18

Journal of the American Society of EchocardiographyJan 18

Association of Impaired Relaxation Mitral Inflow Pattern (Grade 1 Diastolic Function) With Long-Term Noncardiovascular and Cardiovascular Mortality

Cohort study of 1,005 peopleBiomarkers

Paper

Tuesday, January 14

Journal of Obesity & Metabolic SyndromeJan 14

Ratio of Skeletal Muscle Mass to Visceral Fat Area Is a Useful Marker for Assessing Left Ventricular Diastolic Dysfunction among Koreans with Preserved Ejection Fraction: An Analysis of the Random Forest Model

Cross-sectional study of 1,070 peopleVisceral fat area

Paper

Wednesday, January 1

GSA 2024 AbstractJan 1

GLYNAC AND THE AGING MOUSE HEART: SEX-RELATED DIFFERENCES AND OUTCOMES

Experiments in miceInterventions

Paper

Friday, November 29

Physiological ReportsNov 29

Tipping the scale: Effects of physical activity and body composition on cardiac parameters in postmenopausal females

Cross-sectional study of 34 peoplePostmenopause

Paper

Sunday, November 24

Journal of Lipid ResearchNov 24

Lysophosphatidylethanolamine improves diastolic dysfunction by alleviating mitochondrial injury in the aging heart

Experiments in miceDiastolic dysfunction

Paper

Thursday, November 21

CirculationNov 21

Association of Coagulation Factor XI Level With Cardiovascular Events and Cardiac Function in Community-Dwelling Adults: From ARIC and CHS

Cohort study of 4,471 peopleCardiovascular disease

Paper

Monday, November 18

bioRxivNov 18

The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age

Preprint: experiments in miceElamipretide

Paper

Monday, November 4

The Journals of Gerontology, Series ANov 4

Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart

Experiments in miceInterventions

Paper

Thursday, October 10

International Journal of ObesityOct 10

Association of metabolically healthy obesity with risk of heart failure and left ventricular dysfunction among older adults

Cohort study of 6,335 peopleLeft ventricular dysfunction

Paper