Dendritic mushroom and thin spine density

1. PDE2A decreases dendritic mushroom and thin spine density in mice.

   “is paralleled by increased density of dendritic mushroom and thin spines in hippocampal CA3 and dentate gyrus in adult mice.”

   Animalsshown by heterozygous Pde2a knockouthippocampal CA3 and dentate gyrus

   Longevity, enhanced memory, and altered density of dendritic spines in hippocampal CA3 and dentate gyrus after hemizygous deletion of Pde 2a in mice

   Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·27 Nov 2024

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