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Deficits Accumulation Index

There are 2 papers on Deficits Accumulation Index in aging research: 2 observational studies in people. The newest story, Nov 13, 2026: “Frailty predicted persistent fatigue in older breast cancer survivors”.

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4 new papers in 30 daysSee all 56 papers on Deficits Accumulation Index

  • Humans2

Interventions

3

Passive sedentary behavior

upin humans1

1 study

  1. Passive sedentary behavior is linked with higher Deficits Accumulation Index in humans (compared with 2-2.9 h/day) (2.13 (95% CI 0.78, 3.47); P for trend = 0.001).

    “women who spent 3-3.9, 4-4.9 and ≥5 h/day on passive SB showed DA increases of 0.41 (-0.52, 1.35), 1.35 (0.13, 2.57) and 2.13 (0.78, 3.47)”

    Humanscompared with 2-2.9 h/day≥5 h/dayfemales

    Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults

    International journal of epidemiology

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Household physical activity

no changein humans1

1 study

  1. Household physical activity was not clearly linked with Deficits Accumulation Index in humans (adjusted for reverse causation).

    “Household PA showed no effect on subsequent DA after adjusting for reverse causation.”

    Humansadjusted for reverse causation

    Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults

    International journal of epidemiology

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Recreational physical activity

downin humans1

1 study

  1. Recreational physical activity is linked with lower Deficits Accumulation Index in humans (compared with 10-19.9 MET-hours/week) (-0.87 (95% CI -1.59, -0.13); P for trend = 0.006).

    “Compared with participants with previous recreational PA of 10-19.9 metabolic equivalent hours/week (MET-hours/week), average differences in DA index”

    Humanscompared with 10-19.9 MET-hours/week30-39.9 MET-hours/week

    Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults

    International journal of epidemiology

More on Recreational physical activity

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Dec 2025: 0Jan 2026: 2Feb 2026: 0Mar 2026: 0Apr 2026: 2May 2026: 0Jun 2026: 3Jul 2026: 1Aug 2026: 1Sep 2026: 3Oct 2026: 3Nov 2026: 116 papers in 12 months
Journal of Geriatric Oncology

Frailty predicted persistent fatigue in older breast cancer survivors

A longitudinal cohort study of 543 women aged 60 and older linked greater pre-treatment frailty to persistent fatigue after breast cancer.A longitudinal cohort study of 543 women aged 60 and older linked greater pre-treatment frailty to persistent fatigue after breast cancer.

Cohort · 543 peopleBiomarkers
Paper
GeroScience

Low-dose aspirin did not prevent functional decline in older adults

Women assigned aspirin had a small extra decline versus placebo, with an estimated effect of minus 0.006 on the capacity score; men showed no effect.Women assigned aspirin had a small extra decline versus placebo, with an estimated effect of minus 0.006 on the capacity score; men showed no effect.

Randomized trial · 18,581 peopleAspirin
Paper
Age and Ageing

Plant-based diet quality linked to frailty in older adults

Higher overall plant-based diet scores, compared with lower scores, were linked to lower frailty odds, with odds ratios of 0.71 to 0.80.Higher overall plant-based diet scores, compared with lower scores, were linked to lower frailty odds, with odds ratios of 0.71 to 0.80.

Cohort · 8,628 peoplePopulations
Paper
Cancer Epidemiology, Biomarkers & Prevention

Aging measures not consistently linked to cancer in survivors

An observational study of 4,272 childhood cancer survivors found no consistent link between aging measures and later malignancies; median follow-ups were 5.9, 5.0 and 4.9…An observational study of 4,272 childhood cancer survivors found no consistent link between aging measures and later malignancies; median follow-ups were 5.9, 5.0 and 4.9 years.

Cohort · 4,272 peopleBiomarkers
Paper

See all 56 papers on Deficits Accumulation Index

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