Frontiers in Bioscience
Active Vitamin D Insufficiency Accelerates Skeletal Aging via Oxidative Stress and p16-Mediated Senescence
Experiments in miceVitamin D
Papers on Cyp27b1
24 papers
Thursday, January 8
Sunday, October 19
Cellular Signalling
Bmi-1 overexpression mitigates vitamin D deficiency-induced pulmonary fibrosis via TIME pathway
Experiments in miceLung
Monday, February 3
Journal of Orthopaedic Translation
The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis
Experiments in miceVitamin D
Monday, October 21
Journal of Orthopaedic Translation
The senolytic agent ABT263 ameliorates osteoporosis caused by active vitamin D insufficiency through selective clearance of senescent skeletal cells
Experiments in miceSenolytics
Wednesday, September 25
Saturday, February 24
BioFactors
Vitamin D metabolism is altered during aging alone or combined with obesity in male mice
Experiments in miceMechanisms
Wednesday, January 11
Journal of Bone and Mineral Research
Bmi-1 Overexpression Improves Sarcopenia Induced by 1,25(OH)₂ D₃ Deficiency and Downregulates GATA4-Dependent Rela Transcription
Experiments in miceSarcopenia
Sunday, July 31
Wednesday, January 12
Animals
Expression of Renal Vitamin D and Phosphatonin-Related Genes in a Sheep Model of Osteoporosis
Experiments in 18 sheepKidney
Tuesday, December 28
American Journal of Translational Research
Maternal Vit D supplementation in AMA mice and the role of Vit D/VDR signaling in the offspring's cognition
Experiments in miceInterventions
American Journal of Translational Research
1,25-Dihydroxyvitamin D deficiency induces sarcopenia by inducing skeletal muscle cell senescence
Experiments in miceCellular senescence
Sunday, November 28
Thursday, February 18
The Journal of Steroid Biochemistry and Molecular Biology
Altered expression of the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 under the context of prostate aging and pathologies
Experiments in ratsMechanisms
Friday, February 12
Wednesday, May 20
Scientific Reports
Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing
Experiments in miceMuscle
Friday, May 1
International Journal of Endocrinology
Older Age Is Associated with Decreased Levels of VDR, CYP27B1, and CYP24A1 and Increased Levels of PTH in Human Parathyroid Glands
Study in peopleMechanisms
Saturday, March 21
American Journal of Translational Research
1,25-Dihydroxyvitamin D insufficiency accelerates age-related bone loss by increasing oxidative stress and cell senescence
Experiments in miceCellular senescence
Friday, November 15
Journal of Bone and Mineral Research
The Polycomb Protein Bmi1 Plays a Crucial Role in the Prevention of 1,25(OH)₂ D Deficiency-Induced Bone Loss
Experiments in miceBones and joints
Saturday, June 30
Endocrinology
Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance
Experiments in miceMechanisms
Saturday, January 27
Journal of Clinical Biochemistry and Nutrition
The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice
Experiments in miceKL
Thursday, December 29
Ophthalmology
Associations between Serum Vitamin D and Genetic Variants in Vitamin D Pathways and Age-Related Macular Degeneration in the European Eye Study
Cross-sectional study of 4,753 peopleNeovascular age-related macular degeneration
Thursday, October 27
Journal of Bone and Mineral Research
Association Between Single Gene Polymorphisms and Bone Biomarkers and Response to Calcium and Vitamin D Supplementation in Young Adults Undergoing Military Training
Randomized trial in 748 peopleVitamin D
Thursday, January 21
Wednesday, November 14
JAMA
Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes
Cohort study of 1,514 peoplePopulations