CX3CR1

3 papers1 finding

Humans2
Animals1

Associations

1

Postoperative cognitive dysfunction

upin humans1

1 study

CX3CR1 predicts postoperative cognitive dysfunction in humans (AUC 0.72).
“ROC analysis indicated moderate predictive accuracy for each biomarker individually (AUC: ITGAM = 0.78, CX3CR1 = 0.72, iNOS = 0.74)”
Humanspatients undergoing cardiopulmonary bypassserumwithin 6 hours after surgeryn = 246
Serum ITGAM, CX3CR1, and iNOS Early Post-Op Correlate with Postoperative Cognitive Dysfunction in Elderly Cardiac Surgery Patients
Rejuvenation research31 Jul 2026

More on Postoperative cognitive dysfunction

Latest

17 in 12 months

bioRxiv2 Oct

Macrophage-derived VEGFA maintains eye outflow in mice

Deleting Vegfa in CX3CR1-positive macrophages raised intraocular pressure and reduced aqueous humor outflow facility in nine-month-old mice.Deleting Vegfa in CX3CR1-positive macrophages raised intraocular pressure and reduced aqueous humor outflow facility in nine-month-old mice.

Preprint: experiments in miceVEGFA

Angiogenesis26 Sep

Myeloid deficiency of RORα exacerbates lipid dysregulation and laser-induced choroidal neovascularization

Experiments in miceMechanisms

Immunology22 Sep

High-Intensity Interval Training Modulates NLRP3 Inflammasome-Related Expression and Monocyte Subset Distribution in Adults With Obesity: A Randomised Trial

Randomised trial in 109 peopleHigh-intensity interval training

CNS Neuroscience & Therapeutics10 Sep

Sleep Deprivation Induces Glial Dysfunction, Synaptic Loss, Metabolic Imbalance, and Cognitive Impairment in 12-Month-Old Mice: Protective Effects of D30

Experiments in miceCognitive impairment

Neurochemical Research6 Sep

Strain-Specific Cognitive and Neurobiological Vulnerabilities to Social Isolation in Late Middle-Aged Wistar, Wistar-Kyoto, and Spontaneously Hypertensive Rats

Experiments in ratsMechanisms

Cell Reports8 Aug

IL-19⁺ monocytes suppress neuroinflammation and promote neurological recovery in young individuals with traumatic brain injury

Experiments in miceInflammation

Rejuvenation Research31 Jul

Serum ITGAM, CX3CR1, and iNOS Early Post-Op Correlate with Postoperative Cognitive Dysfunction in Elderly Cardiac Surgery Patients

Cohort study of 246 peoplePostoperative cognitive dysfunction

Reproductive Sciences10 Jul

Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women

Cohort study of 20 peopleReproductive system

Virologica Sinica16 May

Immune profile and mitochondrial alterations driven by age and HIV infection: Associations with T-cell senescence in people with HIV receiving suppressive antiretroviral therapy

Cross-sectional study in peopleImmune response

npj Aging8 Apr

Aging effects on emotionality, cognition and brain mononuclear cells in Sprague-Dawley rats of both sexes

Experiments in ratsMechanisms